BPC-157 5MG

BPC-157 5MG

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For this product you will need: BACTERIOSTATIC WATER For reconstitution.

The BPC-157 5MG for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.
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What Is BPC-157 5MG?

BPC-157 is a synthetic derivative of the body protection compound (BPC), a protein found in the stomach. BPC is responsible for the protection of the stomach lining against damage, angiogenesis, and healing through tissue regeneration.

BPC-157, comprised of 15 amino acids, is suspected to retain the healing properties of its parent compounds. Furthermore, research concludes that it might mediate NO release, inhibit infammation and trigger the synthesis of growth factors. Researchers from all over the world are interested in exploring its medicinal properties, especially its healing capacity. On our website, BPC-17 for sale is available for scientific and research purposes.

Structure Of BPC-157 5MG


From Pubchem


Synonyms: BPC-15, Booly protection compound 15
Molecular Weight: 1419.5 g/mol
Molecular Formula: C62H98N16O22
CAS number: 137525-51-0
PubChem CID: 108101

BPC-157 5MG Uses In Research

1. BPC-157 And Angiogenesis

Numerous studies indicate that this man-made compound is involved in angiogenesis, the formation of new blood vessels. In a study, rats suffering from ischemic colitis treated with BPC-157 (10ug/kg) experienced quick restoration of blood supply in the ischemic area [1].

In another study conducted on rats, the inferior vena cava vein was ligated, which commonly results in a disturbance of blood flow, vessel injury and formation of thrombus. Subjects when treated with BPC-157 counteracted these effects and demonstrated redistribution of trapped blood volume [2].

Studies show that its angiogenic effect might be due to the stimulation of VEGFR2, which is a receptor present on the surface of cells that mediates the NO signaling pathway. In a study, increased expression of VEGFR2 was found after BPC-157 treatment in rats with hind limb ischemia that further activated the VEGFR2-Akt-eNOS pathway. On the contrary, administration of dynasore (inhibitor of VEGGR2) didn’t activate the pathway and blocked endothelial tube formation [3].

2. BPC-157 and Wound Healing

Research shows that BPC-157 is involved in the healing of wounds. In a study, the gastroprotective effect of body protection compound 157 was investigated in rats with acute or chronic gastric ulcer. BPC-157 administration via both the intranasal and intragastric routes accelerated ulcer healing and effectively reduced the size of the ulcer. Furthermore, it was observed that continuous BPC-157 treatment induced the rebuilding of glandular epithelium and glandular tissue formation [4].

In another study, intraperitoneal administration of BPC-157 (2ug/kg) improved motor function, reduced lesions in white and grey matter and relieved neuronal damage in rats with spinal cord injury [5]

Research in the alkali burn rat models has shown that topical BPC-157 can speed up wound closure. Moreover, it reveals that possible mechanisms behind this effect might include granulation tissue formation, reepithelialization and deposition of collagen through the ERK1/2 signaling pathway [6]

3. BPC-157 And Recovery from Musculoskeletal Injuries

Research on animal models shows that BPC-157 has the potential to improve performance and recovery from injuries. In a study, BPC-157 was administered through either, intraperitoneal, oral or topical root after the surgical resection in rats. The results found improved healing of transected medial collateral ligament with the treatment, indicating that BPC-157 holds the potential for improving acute ligament injuries [7].

Another study aimed to investigate the possible mechanism by which BPC-157 speed up the healing of the injured tendon. The results showed that BPC-157 accelerated the outgrowth of tendon fibroblasts and it increased the survival of these cells under the H202 stress. It also enhanced the migration and spreading of tendon fibroblast in a dose-dependent manner. Moreover, increased expression of FAk and paxillin was observed, and it was speculated that these proteins might be involved in mediating the recovery of injured tendons [8].

BPC-157 was also found to be effective in accelerating the recovery from transected muscles and muscle-crushed injuries in rats. Plus, it has been shown to counteract the negative impact of corticosteroids in tendon-to-bone healing [9].

4. BPC-157 and Neuroprotection

Various studies show that BPC-157 has a neuroprotective effect. Research conducted on rats showed that this synthetic peptide can counteract the effects of cuprizone, a drug that induces demyelination of nerve fibers and mimic the damage caused by multiple sclerosis, by reducing nerve damage [10].

In another study, intraperitoneal administration of BPC-157 alleviated the effects of MPTP by improving somatosensory orientation, reducing hyperactivity and decreasing motor abnormalities. MPTP is an agent used to mimic the damage caused by Parkinson’s disease [11]

Furthermore, BPC-157 was found to be effective in improving memory, locomotion and coordination and relieving neuronal damage in rats with stroke induced by bilateral clamping. These studies indicate that this synthetic analogue has the potential to treat several central nervous system disorders [12].

5. BPC-157 and TB500

Tb-500 is a synthetic derivative of thymosin beta-4 (Tβ-4), a naturally occurring peptide present in Thymus gland. Research shows that BPC-157 and TB500 aid in the wound healing and may have synergistic effect when combined. As we discussed above, BPC-157 is involved in the growth and migration of fibroblasts [8]. Fibroblasts play an important role in turnover of extracellular matrix. Following the injury, fibroblast become active and transform into myofibroblasts that aid in wound healing process by reducing the size of wound. Migration of fibroblast to area of injury is an important step in the recovery of wound that depends on actin protein [13]. Research shows that Tb-500 is involved in sequestering actin molecules to form filaments that promote cell movement. Further, Tβ-4 is involved in angiogenesis, collagen deposition and inhibits apoptosis and inflammation, thus adding to the medicinal effect of BPC-157 [14].

6. Current Status of BPC-157

Various studies on animal models confirmed the angiogenic effect and healing properties of BPC-157. It has the potential to speed up the recovery of musculoskeletal injuries but is not yet approved by the FDA for clinical use in humans. As an experimental drug, BPC-157 purchase is limited to educational and research institutions. Only buy BPC-157 if you are a licensed researcher.

Referenced Citations

  1. Duzel, A., et al., Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights. World J Gastroenterol, 2017. 23(48): p. 8465-8488.
  2. Vukojević, J., et al., Rat inferior caval vein (ICV) ligature and particular new insights with the stable gastric pentadecapeptide BPC 157. Vascul Pharmacol, 2018. 106: p. 54-66.
  3. Hsieh, M.-J., et al., Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. Journal of Molecular Medicine, 2017. 95(3): p. 323-333.
  4. Xue, X.C., et al., Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats. World J Gastroenterol, 2004. 10(7): p. 1032-6.
  5. Perovic, D., et al., Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats. Journal of Orthopaedic Surgery and Research, 2019. 14(1): p. 199.
  6. Huang, T., et al., Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro. Drug Des Devel Ther, 2015. 9: p. 2485-99.
  7. Cerovecki, T., et al., Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat. Journal of Orthopaedic Research, 2010. 28(9): p. 1155-1161.
  8. Chang, C.-H., et al., The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology, 2011. 110(3): p. 774-780.
  9. Pevec, D., et al., Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application. Med Sci Monit, 2010. 16(3): p. Br81-88.
  10. Klicek, R., et al., Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol, 2013. 64(5): p. 597-612.
  11. Sikiric, P., et al., A behavioural study of the effect of pentadecapeptide BPC 157 in Parkinson's disease models in mice and gastric lesions induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydrophyridine. J Physiol Paris, 1999. 93(6): p. 505-12.
  12. Vukojevic, J., et al., Pentadecapeptide BPC 157 and the central nervous system. Neural Regen Res, 2022. 17(3): p. 482-487.
  13. Li, B. and J.H. Wang, Fibroblasts and myofibroblasts in wound healing: force generation and measurement. J Tissue Viability, 2011. 20(4): p. 108-20.
  14. Kim, J. and Y. Jung, Potential role of thymosin Beta 4 in liver fibrosis. Int J Mol Sci, 2015. 16(5): p. 10624-35.

Certificate of Analysis (COA)


High Performance Liquid Chromatography (HPLC)


Mass Spectrometry (MS)


BPC 157 is a penta-decapeptide composed of 15 amino acids. The body protection compound (BPC), which was found in and isolated from human stomach juice, is represented by a partial sequence. It has been demonstrated in animal experiments to hasten the healing of a wide range of lesions, including muscle, tendon, and strained ligaments. BPC 157 has also demonstrated evidence of protecting organs and helping to avoid stomach ulcers. For the treatment of leaky gut, IBS, gastrointestinal cramps, and Crohn's disease, BPC-157 works systemically in the digestive tract. It is known that this peptide has analgesic properties. According to research, it can speed up the healing of skin burns by increasing blood flow to the injured tissues. BPC-157 significantly accelerates reticulin and collagen formation as well as angiogenesis together with stimulation of macrophages and fibroblasts infiltration representing a potential therapeutic tool in wound healing management. Studies show that the naturally occurring wound repair factor BPC-157 is a strong anti-inflammatory compound. Tß4 is unique among repair factors in that it facilitates endothelium and keratinocyte migration, unlike other repair factors like growth factors. Additionally, it has a very low molecular weight, which enables it to move relatively far through tissues, and it does not adhere to the extracellular matrix. The ability of BPC-157 to control Actin, a protein that builds cells and is essential for cell structure and mobility, is one of the drug's primary mechanisms of action. If you're looking to buy BPC-157 online, you've come to the right place. Our BPC-157 5MG for research offers you the opportunity to investigate the mechanisms and applications of this powerful peptide. Whether you're studying muscle injuries, gastrointestinal disorders, or joint health, BPC-157 holds immense potential for advancing your scientific understanding. When you buy BPC-157 from Element Sarms, you can be confident in its quality and purity. We prioritize stringent quality control measures to ensure that our BPC-157 meets the highest standards. Our product is thoroughly tested for potency and purity, providing you with reliable and reproducible results in your research. Purchasing BPC-157 online is convenient and secure through our user-friendly platform. With just a few simple steps, you can buy BPC-157 and have it delivered directly to your laboratory. We take pride in our commitment to exceptional customer service and discreet packaging to ensure a seamless experience. Unlock the healing potential of BPC-157 in your research endeavors. Buy BPC-157 online today and tap into the regenerative power of this remarkable peptide. Trust our dedication to quality and reliability as you embark on groundbreaking scientific exploration. Note: BPC-157 5MG for sale here and other products are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.
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