Clomiphene 50MG/ML | 30ML with dropper

Clomiphene 50MG/ML | 30ML with dropper

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The Clomiphene 50MG/ML for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested. We are selling Clomiphene with a purity level of 99% with the highest standards of quality. Shake well before research
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What Is Clomiphene 50MG/ML | 30ML with dropper?

Clomiphene, also known as Clomifene or Clomid, is a nonsteroidal triphenylethylene derivative that belongs to the class selective estrogen receptor modulator (SERM). It can act both as an agonist and antagonist of the estrogen receptor ERα depending on the baseline estrogen levels. Clomifene acts on the hypothalamus and causes the release of gonadotrophin-releasing hormones through the negative feedback mechanism. It also triggers the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation.

Clomiphene was first synthesized by chemist Frank Palopoli in 1956. It was approved for the treatment of anovulation in 1967. It has also been shown to restore testosterone levels in hypogonadal men and boost athletic performance. At Elements Sarms, the option to buy liquid clomiphene is restricted to research and educational purposes.

Structure Of Clomiphene 50MG/ML | 30ML with dropper

structure

From Pubchem

IUPAC Name:2-[4-[(Z)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine
Synonyms: Zuclomiphene, Clomifene, Clomid
Molecular Formula: C26H28ClNO
Molecular Weight: 406.0 g/mol
CAS Number: 15690-55-8
PubChem CID: 1548955

Clomiphene 50MG/ML | 30ML with dropper Uses In Research

1. Clomiphene and Infertility

Clomiphene is used for ovulation induction in women who ovulate irregularly due to polycystic ovary syndrome (PCOS) or don’t ovulate at all. It is either used alone or in conjunction with metformin or other insulin sensitizers. A study was conducted to compare the efficacy of clomiphene and metformin in women with PCOS. 626 infertile women with PCOS were randomized to receive either clomifene and metformin alone or a combination of the two. The researchers found that live birth rates were 22.5%, 7.5% and 26.8% among clomifene, metformin and combination therapy groups respectively, concluding superior efficacy of clomifene over metformin [1].

PCOS patients who are resistant to clomiphene citrate might respond to the letrozole plus metformin combination [2]. Research shows that letrozole is associated with higher live birth rates and ovulation than clomiphene [3]. Furthermore, clomiphene has also been shown to improve male infertility. Research shows that it can increase sperm production and motility and is a safe therapy for improving sperm parameters in infertile men [4].

2. Clomiphene and Acromegaly

Acromegaly is characterized by excessive production of growth hormone by pituitary glands that leads to the enlargement of body tissues and organs. Oral estrogens, either alone or in combination with other drugs, have been shown to be an effective therapy for acromegaly. A phase II study was conducted to assess the effect of clomiphene citrate on insulin-like growth factor and testosterone in patients with acromegaly. Six male patients were recruited in this study and clomiphene citrate was added to their previous treatment. The researchers found that IGF-1 serum levels decreased by 44% and testosterone levels increased by 209%. These findings indicate that clomifene should be considered for acromegaly patients who don’t respond to conventional therapies [5].

3. Clomiphene and Secondary Hypogonadism

Hypogonadism is a clinical and biochemical testosterone insufficiency syndrome that affects men. It affects various organs and its symptoms include erectile dysfunction, mood changes, reduced sexual drive and muscular changes. Primary hypogonadism is caused by testicular failure while secondary hypogonadism results from inadequate stimulation of the testes by gonadotrophins due to their reduced serum concentration.

Testosterone replacement therapy is the first choice for the treatment of hypogonadism. However, it is associated with adverse effects such as an increase in estrogen and hematocrit levels, elevated prostate-specific antigen (PSA) levels and serum lipid alterations. Clomiphene citrate is often used for the off-label treatment of male secondary hypogonadism. It occupies estrogen receptors in the hypothalamus and pituitary gland, leading to the release of gonadotropins [6]. A data from retrospective study shows that clomiphene normalized testosterone levels in 53. 2% vs. 46.8% by testosterone replacement therapy [7].

4. Current Status of Clomiphene

Clomifene is a nonsteroidal selective estrogen receptor modulator (SERM) that both acts as an agonist and antagonist. It is approved by the FDA for the treatment of ovulation induction and male infertility. It is also used for the off-label treatment of secondary hypogonadism and is banned by the Word Anti Doping Agency (WADA) as it can boost testosterone. At Elements Sarms, the option to buy liquid clomid is restricted to research and educational institutions. Only buy Clomiphene if you are a qualified researcher.

Clomiphene is a selective estrogen receptor modulator (SERM) widely used in research to study female fertility, ovulation induction, and hormonal therapies. Its ability to regulate estrogen receptors makes it a valuable tool for investigating reproductive processes. Elevate your research with Clomiphene 50MG/ML. At our online store, you can conveniently buy Clomiphene online and explore its potential applications in reproductive studies. When you choose to buy Clomiphene online from us, you gain access to a trusted source for your research needs. We prioritize quality and reliability, ensuring that our products are sourced with maximum purity. Experience the convenience of purchasing Clomiphene online from our user-friendly platform. We offer competitive prices, discreet packaging, and prompt shipping to support your research endeavors. Unleash the potential of Clomiphene 50MG/ML in your studies. Purchase Clomiphene online today and unlock new insights in reproductive research. Note: The Clomiphene 50MG for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested. We are selling Clomiphene with a purity level of 99% with the highest standards of quality.
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