Sermorelin 5MG

Sermorelin 5MG

100 % of 100
  • Buy 5 for $44.99 each and save 10%
  • Buy 10 for $39.99 each and save 20%

FREE Shipping for orders over $200


For this product you will need: BACTERIOSTATIC WATER For reconstitution.

The Sermorelin 5MG for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.
Research Liquids
Research Peptides
PDE5 Inhibitors

What Is Sermorelin 5MG?

Sermorelin is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). It binds with GHRH receptors in the pituitary gland and triggers growth hormone release and production. Besides promoting growth, it has the additional benefit of reducing scarring following a heart attack, increasing bone density, improving renal function and reducing seizure activity.

IFDA approved Sermorelin in 1997 for the treatment of growth hormone deficiency in children. It was sold under the brand name Geref. Later, FDA withdrew its approval in 2008 because of commercial reasons. Currently, scientists are interested in exploring its effect on sleep, brain tumor and heart health. Right now, sermorelin for sale is available for research purposes only.

Structure Of Sermorelin 5MG


From Pubchem

Synonym: Sermorelina, 86168-78-7, Somatoliberin
Molecular Formula: C149H246N44O42S
Molecular Weight: 3357.9 g/mol
CAS Number: 86168-78-7
PubChem CID: 16132413

Sermorelin 5MG Uses In Research

1. Sermorelin and Growth Hormone Deficiency

Because of its growth hormone-releasing properties, it can be used in people with this hormone deficiency. In fact, it is preferred over the administration of synthetic growth hormone (GH). It mimics the process by which the human body naturally produces GH in an episodic and intermittent manner rather than constant levels achieved by injecting GH.

Also, sermorelin is subject to the negative feedback mechanism which involves somatostatin, an inhibitor of growth hormone, to prevent unwanted side effects associated with improper dosing. Further, it can avoid tachyphylaxis, loss of drug response after repeated or continued exposure, unlike exogenous GH administration [1].

2. Sermorelin and Antiaging

Levels of growth hormone and GHRH decline with advancing age. Sermorelin can be effectively used to treat growth hormone deficiency in adults. It stimulates the production of IGF-1 in the liver and increases pituitary preserve, thus preserving the hormone neuroendocrine axis and youthful physiology [1].

In a randomized single-blind placebo-controlled trial, participants involving elderly men and women self-injected placebo for 4 weeks followed by GHRH analog administration for sixteen weeks. GHRG analog administration at night resulted in an acute increase in growth hormone within 10 minutes that lasted for up to 2 hours. This effect was sustained during the course of the whole study. Further, researchers observed elevated IGF-1 and IGFBP3 levels, increased skin thickness and lean body mass. However, only men experienced improved insulin sensitivity and libido, suggesting that the treatment has a more pronounced effect on women than men [2].

3. Sermorelin and Cardiac Remodeling

Research shows that sermorelin can prevent cardiac remodeling and reduce scarring after myocardial infarction. In a study conducted on swine, twenty-five subjects (25 to 30kg) with ischemic cardiomyopathy induced by occlusion of the left descending coronary artery were randomized to either receive a placebo or GHRH analog. The result found that the administration of GHRH analog significantly reduced the size of the infarct and improved diastolic strain. Further, it was suggested that local activation of the GHRH pathway resulted in the repairing process [3].

4. Sermorelin and Sleep

IResearch shows that sleep loss might be related to cognitive decline associated with age. GHRH analog administration has been shown to improve sleep, which might stem from its beneficial effects on cognition [4].

Further, it was suggested that orexin is important for sleep cycle regulation. Studies indicate that the administration of GHRH analogs, sermorelin, can enhance orexin secretion [5].

5. Summary

Sermorelin was first approved for the treatment of growth hormone deficiency in children in 1997. But later, its sale was withheld. Currently, it has been researched for its effect on the treatment of sleep, myocardial infarction and age-related problems. We don’t support its unwarranted medical use and offer sermorelin purchase only for research and educational institutions. So if you are a researcher looking to explore its potential therapeutic use, buy sermorelin from Element Sarms.

Certificate of Analysis (COA)


High Performance Liquid Chromatography (HPLC)


Sermorelin Acetate, also known as GRF 1-29, is a Growth Hormone Releasing Hormone (GHRH) produced by the brain that stimulates the production and release of Growth Hormone (GH). Sermorelin Acetate was first developed in the 70s, which is thought to be the shortest fully functional fragment of GHRH and has been used as a test for Growth Hormone secretion. It is often used extensively in Anti-aging Therapy along with Testosterone in men. Sermorelin Acetate affects a more primary source of failure in the GH neuroendocrine axis, has more physiological activity, and its use for adult hormone deficiency is not restricted. Compared to human Growth Hormone (hGH), Sermorelin Acetate is a growth hormone secretagogue, which means that it stimulates the pituitary gland to produce and secrete growth hormone. Also, Sermorelin Acetate and Modified GRF 1-29 contains 29 amino acids whereas hGH is a larger molecule containing 191 amino acids.
Write Your Own Review
You're reviewing:Sermorelin 5MG
Your Rating
Product List
Research Liquids
Research Peptides
PDE5 Inhibitors