Epithalon 10MG

Epithalon 10MG

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For this product you will need: BACTERIOSTATIC WATER For reconstitution.

The Epithalon 10MG for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.
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What Is Epithalon 10MG?

Epithalon is a synthetic tetrapeptide that produces the same effect as epithalamin, a natural polypeptide produced by pineal gland. It was first developed by Professor Vladimir Khavinson, a Russian scientist, in 1980. Its main function is to enhance the production of telomerase, an enzyme that helps cell produce telomers.

Telomers promote the stability and integrity of chromosomes by preventing the loss of essential DNA sequences during cell division. But as people age, telomere length shortens, and the progressive shortening of telomers affects the health and lifespan of humans. Further, it is involved in DNA regulation, and melatonin production and shows significant effects against cancer and some infectious diseases.

Epithalon as a telomerase production booster is a subject of interest for scientists across the globe for its potential antiaging properties. If you are looking to buy epithalon, it’s important to note that it’s not yet approved by FDA, epithalon for sale is currently available for only experimental and research purposes.

Structure Of Epithalon 10MG


From Pubchem


IUPAC Name: (4S)-4-[[(2S)-2-aminopropanoyl] amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl] amino]-5-oxopentanoic acid
Synonyms: Epithalone, alanyl-glutamyl-aspartyl-glycine, epitalon, epithalon
Molecular Formula: C14H22N4O9
Molecular Weight: 390.35 g/mol Sequence: Ala-Glu-Asp-Gly
CAS number: 307297-39-8
PubChem CID: 219042

Epithalon 10MG Uses In Research

Epithalon and Antiaging Different scientific studies indicate that epitalon can prolong the lifespan and delay the aging process. A study found that epitalon preparation when added in the nutrient medium at the developmental stage can increase the mean life span of adult Drosophila Mongoster by 11-16% [1]. Another research on Swiss-derived SHR mice concluded that this tetrapeptide slows down the age-related declining estrous function and can lessen the occurrence of chromosomal abnormalities in bone marrow [2].Similarly, one in vitro experiment found that epitalon can slow down the aging process of oocytes. Furthermore, it reduced the level of ROS (free radicals that can damage healthy cells) in aged oocytes, which explains a possible reason for its antiaging effect. [3]. Apart from omitting  free radicals, it is involved in the activation/production of telomerase, as discussed above. One in vitro study on human somatic cells confirmed the telomerase-inducing activity of epithalon. Further, it suggested the possible role of epitalon in prolonging lifespan in the individual cell and the whole organism [4].

Epithalon and Cancer Epithalon has been studied for its antitumor activity. Several studies show that epitalon tetrapeptide can stop and prevent the development of tumors in rats. Further, it suggested that downregulation of HER-2/neu gene expression might be responsible for the anticancer activity of this peptide[5, 6]. In a study, epitalon reduced the development of mammary tumors in HEN/u2 mice and decreased the size of lung metastases [7]. epitalon has also been shown to stop the initiation of breast carcinogenesis in these mice. An article suggests that epitalon, along with epithalamine, might be useful in the prevention of breast cancer in women who are at risk [8].

Epitalon and Skin Health One in vitro study involving the organotypic cultures of tissues from the skin of animals suggests that epitalon can be used in cosmetics to strengthen and restore the skin structure. This effect can be explained based on its antioxidant and telomerase-inducing activity, which slows down the aging of the skin and improve overall appearance [9]. Furthermore, one article suggests that it suppresses caspase-dependent apoptosis (decreases caspase activity responsible for programmed cell death) that increases during the process of aging [10].

Epitalon and Cardiovascular Effects In a 12-year randomized clinical study, patients treated with epithalamine showed improved functional cardiovascular health and increased exercise tolerance. Plus the cardiac mortality was twice less in patients treated with peptide than those in the control group.[11]. Moreover, another clinical study demonstrated that epithalmine improved lipid metabolism and arterial blood pressure in women with ischemic heart disease and hypertension [12].


Epitalon is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly. After its discovery in 1980, it gained the attention of different scientists for its antiaging properties. Various studies conducted on different animal models speak for its positive effect on skin health, the cardiovascular system and cancer cells. Further research is needed to confirm its safety and efficacy for approval by FDA, till then epithalon purchase is available for research purpose only.

Referenced Citations

  1. Khavinson, V.K., D.M. Izmaylov, L.K. Obukhova, and V.V. Malinin, Effect of epitalon on the lifespan increase in Drosophila melanogaster. Mechanisms of Ageing and Development, 2000. 120(1): p. 141-149.
  2. Anisimov, V.N., et al., Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology, 2003. 4(4): p.193-202.
  3. Yue, X., et al., Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro. Aging (Albany NY), 2022. 14(7): p. 3191-3202.
  4. Khavinson, V., I.E. Bondarev, and A.A. Butyugov, Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med, 2003. 135(6): p.590-2.
  5. Anisimov, V.N., V.K. Khavinson, I.G. Popovich, and M.A. Zabezhinski, Inhibitory effect of peptide Epitalon on colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. Cancer Letters, 2002. 183(1): p. 1-8.
  6. Kossoy, G., et al., Epitalon and colon carcinogenesis in rats: Proliferative activity and apoptosis in colon tumors and mucosa. Int J Mol Med, 2003. 12(4): p. 473-477.
  7. Anisimov, V.N., et al., Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. International Journal of Cancer, 2002. 101(1): p. 7-10..
  8. ÇEVÍK, H., et al., Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: Both receptor and non-receptor-mediated processes. Journal of Gastroenterology and Hepatology, 2005. 20(2): p. 294-303.
  9. Chalisova, N.I., et al., Short peptides stimulate cell regeneration in skin during aging. Advances in Gerontology, 2015. 5(3): p. 176-179.
  10. Lin'kova, N.S., et al., Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro. Bull Exp Biol Med, 2016. 161(1): p. 175-8..
  11. Korkushko, O.V., V. Khavinson, V.B. Shatilo, and I.A. Antonyuk-Shcheglova, Geroprotective effect of epithalamine (pineal gland peptide preparation) in elderly subjects with accelerated aging. Bull Exp Biol Med, 2006. 142(3): p. 356-9..
  12. Merkur'eva, G.A. and G.A. Ryzhak, [Effect of the pineal gland peptide preparation on the diurnal profile of arterial pressure in middle-aged and elderly women with ischemic heart disease and arterial hypertension]. Adv Gerontol, 2008. 21(1): p. 132-42.

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A peptide called epithalon is utilised to control the cell cycle by increasing telomerase activity. The peptide's amino acids are organised as follows: Alanine, Glutamate, Asparagine, and Glycine. Studies on the impact of Epithalon on the inhibition of spontaneous mammary tumours and spontaneous carcinogenesis have been conducted in animals. Epithalon's mode of action is demonstrated by studies to involve the suppression of oncogene expression and alteration of telomerase activity. If you're seeking to buy Epithalon online, Element Sarms is the right place. Our Epithalon 10MG for research offers you the opportunity to delve into the mechanisms and applications of this remarkable peptide. Whether you're studying age-related diseases, exploring its impact on cellular senescence, or investigating its potential as an anti-aging intervention, Epithalon holds immense promise for advancing your scientific understanding. When you buy Epithalon from us, you can be confident in its quality and purity. We prioritize stringent quality control measures to ensure that our Epithalon meets the highest standards. Our product is thoroughly tested for potency and purity, providing you with reliable and reproducible results in your research. Purchasing Epithalon online is convenient and secure through our user-friendly platform. With just a few simple steps, you can order Epithalon and have it delivered directly to your place. We pride ourselves on exceptional customer service and discreet packaging to ensure a seamless experience. Unlock the anti-aging potential of Epithalon in your research endeavors. Buy Epithalon online today and embark on a journey towards understanding cellular rejuvenation and longevity. Trust our dedication to quality and reliability as you pave the way for groundbreaking scientific exploration. Note: Epithalon 10MG for sale here and other products are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.
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